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Baek IJ, Seo DS, Yon JM, Lee SR, Jin Y, Nahm SS et al
Sex differences in markers of oxidation and inflammation
On one hand, IBD can lead to dysregulation of adipokines, shifting the balance towards a pro-inflammatory state, on the other hand obesity and higher BMI are associated with higher risk of developing IBD and worse clinical outcomes, particularly for UC
These effects of macrophage produced NO explain, to a large degree, the cytotoxic and cytostatic effects of NO on invading parasites as well as on certain tumor cells
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