Phase 2 trial data published in 2023 showed participants receiving the highest retatrutide dose lost an average of approximately 24 percent of body weight over 48 weeks, which exceeded results seen with dual-agonist medications in comparable timeframes
Int J Cancer 150:11341140
You should contact your GP if you experience: New or worsening acne after starting GLP-1 treatment, particularly if it is severe, painful, or affecting your quality of life Signs of skin infection , such as increasing redness, warmth, swelling, or pustular lesions that may indicate secondary bacterial infection Scarring or post-inflammatory hyperpigmentation that concerns you Psychological distress related to skin changes, as acne can significantly impact mental wellbeing Your GP can assess whether your acne requires specific dermatological treatment, which may include topical therapies (such as benzoyl peroxide, topical retinoids, or topical antibiotics), oral medications (including oral antibiotics or, in appropriate cases, hormonal treatments), or referral to dermatology services for more complex cases
The antioxidant property of Sp was however, found to be insensitive to depletion of glutathione by BSO, which generally causes loss of cellular antioxidant function and higher ROS (Fig