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For patients who may not have achieved optimal results with dual agonists, or those with unique comorbidities like advanced non-alcoholic fatty liver disease (NAFLD), the introduction of Retatrutide is not just an incremental improvement, it is a re-evaluation of treatment goals

It promotes arterial vasodilation by binding GLP-1R in endothelial cells and releasing NO [69]

Managing Side Effects Its important to work with your healthcare provider to manage side effects, especially in the early stages of treatment

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