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Earlier meta-analyses did report a small on-medication motor benefit, roughly one to three points, but that effect is heterogeneous and fragile: in at least one pooled analysis, it lost statistical significance once the lixisenatide trial was removed [8]

There is no guarantee on what you are getting and what you are putting in your body

Exposure to SGLT2 inhibitors from postnatal day 21 to 90, the period functionally coinciding with the late second and third trimesters of human pregnancy regarding kidney development, caused dilatation of the renal pelvis and tubules ( Table 2 )

Pierre-Louis: That said, the flip side, you know, these drugs are not a panacea, and we are finding some things that are maybe concerning