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Pickart and colleagues have been central to GHK-Cu research since its initial isolation from human albumin in the 1970s
A healthy, unstressed cell maintains a vast majority of its glutathione pool in the reduced state, typically sustaining a GSH-to-GSSG ratio of greater than 10:1, and often up to 100:1 in the cytosol
PMID 18779510
Even then, the drugs didnt meet the cost-effectiveness threshold. That threshold is typically defined as less than $100,000 per quality-adjusted life year (QALY) a standard tool health economists use to compare the value of medical treatments
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