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A1C reduction of 1.7-2.0% across doses at 40 weeks
Retatrutide is also known as LY3437943 (Development code name), and Triple Agonist Peptide (GLP1/GIP/Glucagon)
It has been posited that these changes in autonomic function could arise from crosstalk between the gastrointestinal tract and the central nervous system (121) generated by a neuro-inflammatory reflex (122) arising from the gut microflora
Benefits would correspond to progressive weight loss, better glycemic control, and reduced inflammation rather than rapid pharmacological effects
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