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Recent studies have observed that cepharanthine is capable of inhibiting the interaction between TSHR.132 (TSH receptor peptide) and HLA-DR1-Arg74, thus blocking T cell activation and cytokine response in a Graves disease-relevant humanized mouse model expressing HLA-DR3 (Li et al
(UNEP/POPS/COP.12/32)
Samples were centrifuged (1 min, 2000 rpm), transferred to a new tube, and centrifuged again (15 min, 4 C, 14 krcf)
While these compounds have been studied for antioxidant activity in laboratory settings, robust clinical evidence specifically supporting skin benefits in humans is limited
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