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Reconstitution considerations for 15 mg dosing If you receive tirzepatide as a lyophilized powder (a freeze-dried cake in a vial), you need to reconstitute it before drawing your dose

JAMA 315, 801810

The same large randomized clinical trials that showed positive cardiovascular results in subjects with type 2 diabetes also reported retinopathy complications as secondary outcomes

GLP-1 receptor agonists are currently prescribed for people with type 2 diabetes, those with obesity (defined as individuals with a BMI of 30 or higher, or a BMI of 27 with obesity-related health conditions such as hypertension or high cholesterol),