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We previously showed the presence of mitochondrial dysfunction as early as P15 in the motor cortex, but more precisely in the CSMN of TDP-43 A315T mice 17 , one of the best characterized mouse models of TDP-43 pathology 16,19,33,34

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Protective effects of sulforaphane preventing inflammation and oxidative stress to enhance metabolic health: a narrative review

Depolarization of pericytes can also result from neuronal transmitters like NA, ATP, and Ang2 binding to their corresponding receptors on pericytes, as well as from astrocytic AA entering pericytes [102, 103]