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Higher NNMT activity means more nicotinamide gets shunted away from NAD+ production
The result is a 16-amino acid peptide that stimulates lipolysis through beta-3 adrenergic receptors on fat cells, without triggering IGF-1 elevation, insulin resistance, or the growth-promoting effects that make full HGH problematic for long-term metabolic use
5-Amino-1MQ is a synthetic compound currently being studied for its interaction with an enzyme called NNMT (nicotinamide N-methyltransferase)
Long-term evidence beyond 24 weeks is limited
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