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In bone, GLP-1 binding to its receptor promotes bone marrow mesenchymal stem cell osteoblast differentiation and inhibits its differentiation into fat cells, thereby promoting bone formation and improving osteoporosis [15]
Portion control becomes naturally easier with tirzepatide due to enhanced satiety signals, but conscious attention prevents both overeating (which triggers discomfort) and undereating (which risks nutritional deficiency)
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