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For a 220-pound person, this translates to roughly 33 pounds lost with semaglutide versus 11-18 pounds with Saxenda
Participants on Mounjaro have achieved average weight reductions of up to 20.9% of their body weight in some high-dose arms over 72 weeks (e.g., 19.5% for a 10mg dose and 20.9% for a 15mg dose)
For peptides, threshold varies by endpoint
The Bottom Line Semaglutide changes the gut environment and raises the bar for what a probiotic needs to survive and deliver
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