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Suicidality concerns: what we know now Regulatory reviews by the FDA and EMA have not found evidence that GLP-1s cause suicidal thoughts or behaviors, though monitoring continues (FDA, 2024
Indeed, several studies have demonstrated that aberrant IGF signaling plays a critical role in the pathogenesis and progression of several types of cancer, including lung, breast, colon, prostate, ovary, pancreas, and thyroid ( Nevertheless, data coming from observational studies are still conflicting and inconclusive, since some authors observe an association between insulin therapy and increased cancer risk (Tseng, 2019
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Start with doses at the lower end of the dosing range
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