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Weight regain of 15+ lbs from lowest post-surgical weight Plateau before reaching goal weight despite adherence Persistent hunger that interferes with maintenance At least 12-18 months post-surgery Willing to commit to monitoring and follow-up No contraindications to GLP-1 class medications Less Ideal Candidates Patients within their first year post-surgery generally should not start Retatrutide

If fat loss stalls despite maintained caloric deficit, the issue is rarely dosage insufficiency