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Given the established clinical use of GLP-1RAs for the treatment of T2DM, preclinical and clinical research was centered largely around DR, which suggested the neuropathologic protective effects of GLP-1 are due to downregulation of NF-B, proinflammatory cytokines such as TNF-alpha and IL-1beta, and VEGF
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For diabetes management, the maintenance dose ranges from 0.5 mg to 2 mg weekly, while weight management protocols may use doses up to 2.4 mg weekly
These include: Heart Health Some forms of L-carnitine, like propionyl-L-carnitine, have been studied for improving heart health, particularly in people with carnitine deficiency[3]
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