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The gastrointestinal adverse effects are attributed to the GLP-1 activity these medications produce and there are no therapeutic measures for improving said symptomatology.42,7173 Therefore, the best measure to consider in this group of patients is to use the drug that has less association with gastrointestinal adverse effects
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Patients should take the tablet immediately upon waking with a small amount of water and avoid food or other medications for at least 30 minutes
The two-way ANOVA results of GFAP immunostaining in IL-PFC showed no significant effect of drug, treatment and drug * treatment interaction factors (F (1, 25) = 0.03, p = 0.849: F (1, 25) = 0.34, p = 0.563
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