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Tsaousidou E, Paeger L, Belgardt BF, Pal M, Wunderlich CM, Brnneke H, Collienne U, Hampel B, Wunderlich FT, Schmidt-Supprian M, Kloppenburg P, Brning JC (2014) Distinct roles for JNK and IKK activation in Agouti-related peptide neurons in the development of obesity and insulin resistance
WHO expands essential medicines list to include GLP-1 agonists and Cystic Fibrosis therapies Key Takeaways: The World Health Organization (WHO) has added GLP-1 receptor agonists, rapid-acting insulin analogues, and innovative cancer therapies to its 2025 Essential Medicines Lists (EMLs), signalling their importance in global diabetes and oncology care
For example, human umbilical MSCs pretreated with IL-1 can transfer miR-146a via exosomes to macrophages, promoting their polarization to the M2 phenotype, thus enhancing anti-inflammatory effects (Song et al., 2017)
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