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Mar 14 2025;23(1):211

Subsequently, cytochromes P450 (CYP79s) catalyzes the conversion of the amino acid derivatives to aldoximes, oxidized later by CYP83s into nitrile oxides, transformed to thiohydroximates via glutathione (GSH) S-transferases (GSTFs) and the C-S lyase (SUR1) reaction, and finally converted to the GL core structure by S-glucosyltransferases (UGT74s) and sulfotransferases (SOTs) (Figures 35)

Reaction of these electrophiles with DNA can sometimes result in cancer through the mutation of genes, such as oncogenes or tumor suppressor genes

You have probably heard the word antioxidant hundreds of times, but glutathione is different