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What makes the evidence compelling for legal purposes is the consistency across multiple independent studies, the dose-response relationship (higher risk with longer use), and the fact that non-diabetic users taking the drugs solely for fat loss show the highest risk increase

While the early data is exciting, it has not yet been approved for medical use and is only available through clinical studies

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Lysates were cleared by centrifugation (14,000 g , 10 min, 4 C) and incubated with anti-FLAG antibody for 1 h at 4 C with gentle rotation