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In the serum, Fe 2+ is oxidized by ceruloplasmin to Fe 3+ and then binds with transferrin (TF) to form a TFFe 3+ complex, which is endocytosed through the cell membrane transferrin receptor 1 (TFR1) (Frazer and Anderson, 2014)
Anti-inflammatory gene regulation Inflammation is a double-edged phenomenon
Alzheimers Dement (2015) 11(6):60821.e7
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