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2026 Jan;15(1):e70001

What Remains Essential With or Without Medication Thorough medical evaluation and ongoing clinician supervision Sustainable diet and physical activity changes Patience with realistic timelines, as trials evaluated outcomes over 64 weeks or longer Awareness of potential risks and side effects Individual results vary widely based on adherence, lifestyle factors, medical history, and biological response

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GLP-1 medications included under the Medicare Bridge program: Zepbound a once-weekly needle injection