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The clinical trial participants who achieved 24-28% body weight reduction were not just taking the drug
In conclusion, the reason why the ApoE 4 allele increases the risk of developing AD is not because it interacts with amyloid or tau but because of the physiological roles it plays in being less effective in supporting insulin signaling and energy utilization by neurons and in activating the inflammation response more than the other two alleles
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Many patients notice initial improvements in appetite control and energy levels within the first few weeks
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