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Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., & Sun, G
For semaglutide, the main concerns include pancreatitis (rare but documented), gallbladder events (including gallstones, particularly during rapid weight loss), and a theoretical concern about medullary thyroid carcinoma based on rodent studies
It works by stimulating insulin release (insulin secretion) when blood sugar levels are elevated, reducing glucagon secretion from the pancreas, and slowing gastric emptying to reduce appetite and enhance feelings of fullness