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Weight loss was associated with improvements in: Blood pressure Lipid profiles Sleep apnoea Joint pain Quality of life These findings led regulatory bodies to approve semaglutide (Wegovy) and tirzepatide (Zepbound) for obesity treatment, even in the absence of diabetes signalling a paradigm shift in how weight and metabolic risk are medically managed
That's why Ali recommends that all of his weight loss patients focus on eating plenty of protein and vegetables
However, the critical limitation remains the near-complete absence of human clinical trial data
Additional questions patients often ask: Weight can return after stopping treatment, especially if appetite increases and habits are not maintained
