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Development Physiological role of GLP-1 in humans Separately from the work taking place in Copenhagen another team in London, based at the Royal Postgraduate Medical School at Hammersmith Hospital, had begun to assess the physiological role of GLP-1 directly in humans
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Future research should prioritize the development of next-generation agonists, explore combination therapies, and integrate precision medicine approaches to optimize patient outcomes
doi: 10.3389/fnut.2024.1509577 Received 11 October 2024 Accepted 02 December 2024 Published 16 December 2024 Volume 11 - 2024 Edited by Shaohua Qi, Houston Methodist Research Institute, United States Reviewed by Ying-yuan Lu, Peking University, China Ma Ying, China Academy of Chinese Medical Sciences, China Kexin Gai, Northwestern University, United States Ting Wu, University of Texas Health Science Center at Houston, United States Updates Copyright 2024 Xing, Du, Li, Wang, Zhang, Gao, Han, Sun, Sun, Du, Hu, Yu and Qin
Tirzepatide has been studied across a wide range of body weights (from 40 kg to over 200 kg), with only minor differences in exposure that are not clinically significant enough to warrant dose modifications
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