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The central clinical idea: toxic overload may affect mood when oxidative stress, inflammation, mitochondrial strain, glutathione depletion and impaired clearance reduce the brains biochemical resilience
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Timing: Why 30 to 60 Minutes Before Bed Matters DSIP's plasma half-life is 15 minutes, but the neuroendocrine cascade it triggers takes 20 to 40 minutes to fully engage
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