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Elizabeth Rebello, one of the panelists, said during the first day of deliberation

A decrease in glutathione levels can lead to a decrease in methylation, which can have serious implications for cellular health and function

Some disorders of intracellular cobalamin metabolism (cblC, cblD-MMA/Hcy, cblF, and cblJ) do not only compromise the synthesis of methylcobalamin, but also the synthesis of adenosylcobalamin, cofactor of the enzyme methylmalonyl-CoA mutase, leading to elevated concentrations of both tHcy and methylmalonic acid (MMA)

In addition, cysteamine eyedrops can dissolve corneal cystine crystals within months