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Semaglutide compares well with sitagliptin AT THE ADA ANNUAL SCIENTIFIC SESSIONS NEW ORLEANS Semaglutide, a GLP-1 agonist for type 2 diabetes thats dosed weekly, was superior to daily sitagliptin in improving glycemic control and reducing body weight in people who are also on metformin and/or thiazolidinediones (TZDs), based on results from a phase III trial
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These reductions appear to result from weight loss, improved insulin sensitivity, and potentially increased sodium excretion