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The weighted mode is based on the assumption that a plurality of genetic variants are valid instruments, i.e., no larger subset of invalid instruments estimating the same causal parameter than the subset of valid instruments exists [44]

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Earlier in 2025, the same research group published papers demonstrating that although GLP-1 drugs deliver impressive long-term health improvements, their prices far exceeded accepted thresholds for cost-effectiveness

This means they: Stay with your practice longer Are more willing to explore multiple treatments Often book follow-ups and combination therapies When your team knows how to support these patients, you can turn high-value clients into long-term revenue