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Current Pharmaceutical Design, 2010, 16(10):1224-1234

Key characteristics A small molecule (quinolinium derivative), NOT a peptide Acts as an inhibitor of the enzyme NNMT Rationale is preservation of NAD+ / methyl-donor balance in metabolically active tissue Evidence to date is largely preclinical (cell and rodent models) No approved human therapeutic indication Reported research dosing reference only Educational reference, not dosing guidance