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Methods Design This was a qualitative study using individual semi-structured interviews
One area that has attracted academic discussion, press coverage, and significant biotechnology/pharma R&D investment is concern about undesirable, collateral skeletal muscle mass (SMM) loss, and presumably by extension, loss of strength and function in people taking GLP-1 medications
Body composition shifts are real but modest, typically a few pounds of visceral fat reduction and improved muscle definition over months, not the dramatic scale changes seen with semaglutide or tirzepatide
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