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Theres also been concern that GLP-1 drugs might increase the risk of a rare form of thyroid cancer in patients taking immune-suppressing drugs to prevent transplant rejection, researchers added

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In parallel, advances in peptide chemistry and structural biology have enabled the design of aggregation inhibitors, receptor-selective neuropeptide analogues, and cell-penetrating or brain-targeted peptide conjugates that modulate key pathways, including proteostasis, insulin and incretin signaling, neurotrophic support, and microglial activation