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Effect of bimagrumab on thigh muscle volume and composition in men with casting-induced atrophy
Riley, D
doi: 10.1016/j.imlet.2004.01.014 132 HuangQDuanLQianXFanJLvZZhangXet al
Initially, when insulin resistance occurs, pancreatic bcells compensate by secreting more insulin to maintain normal glucose metabolism, but as the disease progresses, pancreatic b cell function deteriorates, insulin secretion significantly decreases, blood sugar cannot return to normal baseline levels, leading to metabolic disorders, including glucose and lipid abnormalities, and metabolic diseases such as T2DM (Warram et al., 1990
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