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In Phase 2 obesity trials, retatrutide produced approximately 24% mean body-weight reduction at 48 weeks at the 12 mg dose the largest weight-loss effect reported for any GLP-1-class compound to date
( c ) Pearsons correlation of TOM20 and VDAC2 expression in tumour areas, where each dot represents mean staining per mouse
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Weeks 17 and beyond reach the 12mg maintenance dose if tolerated
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