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Recommended protocol: Washout: 25 to 30 days Starting dose: 2mg weekly Week 5: escalate to 4mg Week 9: escalate to 8mg Week 13: escalate to 12mg based on response This accelerated schedule saves 4 weeks compared to the standard titration
Most patients notice appetite reduction within the first week, with significant weight loss typically beginning after 4-8 weeks of treatment
Many members use GLP-1s for 312 months, then transition to lifestyle-based maintenance supported by continued Healthspan coaching and monitoring
doi:10.1136/emj.20.4.366
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