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On the Cagrilintide side, the value of the standalone phase 2 trial is that it isolates the amylin effect from any GLP-1 contribution
J Med Chem 58:73707380 Gotfredsen CF, Molck AM, Thorup I et al (2014) The human GLP-1 analogs liraglutide and semaglutide: absence of histopathological effects on the pancreas in nonhuman primates
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Therefore, it is biologically plausible that a person losing significant fat with medication could experience the same redistribution of fat-stored compounds observed with other forms of weight loss
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