Increased urination accompanied by the following symptoms may indicate inadequate diabetes control: Excessive thirst (polydipsia) : The combination of increased urination and persistent thirst suggests hyperglycaemia Unexplained weight loss : Despite Ozempic's weight-reducing effects, rapid or excessive weight loss with increased urination may indicate poor glycaemic control Fatigue and blurred vision : These symptoms alongside polyuria suggest elevated blood glucose levels Fruity-smelling breath : This may indicate diabetic ketoacidosis, a medical emergency requiring immediate attention - call 999 or go to A&E Other concerning presentations include: Urinary tract infection (UTI) : Increased frequency accompanied by burning sensation, cloudy or strong-smelling urine, lower abdominal pain, or fever requires prompt medical assessment
The hypoglycemia stimulates glucagon release from the pancreas and epinephrine release from the adrenal glands leading to increased fatty acid release from adipose tissue
While no direct contraindication exists for concurrent use, the absence of controlled trials means safety and efficacy remain inadequately characterized
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