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ESC Heart Fail 5(6):10351043 Lepore JJ, Olson E, Demopoulos L, Haws T, Fang Z, Barbour AM, Fossler M, Davila-Roman VG, Russell SD, Gropler RJ (2016) Effects of the Novel Long-Acting GLP-1 Agonist, Albiglutide, on Cardiac Function, Cardiac Metabolism, and Exercise Capacity in Patients With Chronic Heart Failure and Reduced Ejection Fraction
Concentrated urine and reduced urinary frequency create conditions that may increase susceptibility to bacterial colonisation of the urinary tract
The American Diabetes Association guidelines emphasize individualized treatment approaches that balance efficacy with tolerability
Key red flags include pregnancy (no safety data, so contraindicated), active cancer (caution due to growth effects), autoimmune disorders, or organ failure
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