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Previous research suggests that NAC may promote the nuclear translocation of Nrf2 [14] or activate NF-B signaling pathways [63], leading to increased expression of SOD and GSH-Px, thereby reducing excessive ROS that damage mitochondria in mouse oocytes

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All patients operated in the fast-track protocol receive standardised multimodal opioid-sparing analgesia, including local infiltration analgesia for TKA/UKA, non-steroidal anti-inflammatory drug (NSAID)/cyclooxygenase (COX)-2 inhibitors, paracetamol and high-dose glucocorticoid [15] along with postoperative nausea and vomiting prophylaxis including ondansetron