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Rutin-loaded polydopamine nanoparticles (PPR NPs) release iron chelators in acidic environments, reducing intracellular unstable iron pool (LIP) levels, thereby inhibiting ferroptosis and alleviating RIRI [57]
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It suggested a non-linear dose-response relationship, indicating that a daily intake of 2000 mg (oral) of L-Carnitine could provide the maximum effect in reducing body weight among adults, particularly those with overweight or obesity
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