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If there is any hormonal advantage, it would almost certainly be in the context of an individualized protocol involving lifestyle, diet, and evidence-based medical treatment
After exclusions, the final cohort comprised 69,047 short-term users and 133,387 long-term users
One case report described a patient with polycystic ovarian syndrome (PCOS) receiving long-term metformin treatment
They offer the flexibility of dosage adjustments and a lower risk of immediate surgical complications
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