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Patients may see hollow cheeks, sagging skin, deeper wrinkles, or a gaunt appearance

Secretagogues and Body Composition Beyond incretin-based peptides, another class often discussed in fat-loss research is growth hormone secretagogues , including: CJC-1295 Ipamorelin Tesamorelin These peptides stimulate endogenous growth hormone release via GHRH or ghrelin receptor pathways

2 WW also cites internal data from a study of 3,250 Clinic patients, reporting that those prescribed a GLP-1 lost an average of 21% of their body weight at 12 months