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This combination isn't appropriate for patients who are pregnant or nursing, individuals under 18, those with active malignancies, or patients with contraindications to tirzepatide (medullary thyroid carcinoma history, MEN2 syndrome, pancreatitis history)
Layer two consists of formulation patents covering concentration, buffer systems, and preservatives, filed at Phase II (year 5 to 7, expires year 25 to 27)
doi: 10.1371/journal.pone.0202134
This isnt a formulation difference or a molecular difference its purely a dosing difference
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