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6J, IC261 treatment led to decreased p-Sec24C expression and attenuated expression of SLC7A11 at the PM level in PDCs with high expression of VRK2

Pharmacol Res Commun 14:6172 Prescott L, Roscoe P, Wright N, Brown S (1971) Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage

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Conclusion and outlook Over the past decades, research has elucidated the classification, signaling mechanisms, and diverse biological roles of PRRs, underscoring their significance in both health and disease contexts