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We first examined the impact of 5FU treatment on mitochondrial abundance in the well-characterized CRC cell model HCT116
Combination therapy with acarbose and metformin has been demonstrated, in multiple studies, to be more effective for the control of blood glucose than treatment with either drug alone (Mooradian 1999
This process effectively pre-conditions the cell to withstand subsequent, more severe insults, a mechanism that mirrors the protective effects of ischemic preconditioning (Wu et al., 2023)
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