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COP1 and DET1 cooperate to promote polyubiquitination of c-Jun The role of the RING finger in COP1 has been intriguing, as it can independently bind E2 enzymes 51,52 , making it appear as a redundant subunit within the CULLIN4 DET1-COP1 complex
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If there is enough B12 at work in the cells, it keeps these two substances down, and the results of these tests will be low
The absence of many reports may reflect limited systematic monitoring rather than an absence of risk
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