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Considering A2780 and A2780 cisR cells under hypoxia upon carboplatin exposure, cysteine was advantageous for A2780 cisR but not for A2780 parental cells, reinforcing that cysteine accounts for the selective process of platinum resistant ovarian cancer cells

AMSTAR 2 assessments indicate that the existing evidence is limited by methodological shortcomings, including incomplete reporting of excluded studies, suboptimal literature search strategies, and insufficient evaluation of how bias in primary studies may influence meta-analytic estimates

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