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However, the discontinuation rates for Danuglipron across different doses were over 50%, significantly higher than the approximately 40% observed in the placebo group, indicating poor tolerability in some patients

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A 2018 review in the International Journal of Molecular Sciences compiled the regenerative-research findings against the backdrop of transcriptomic profiling that flagged thousands of human genes as up- or down-regulated under GHK-Cu exposure (PMID 29986520)