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Research Models & Proposed Pathways Evidence Level & Research Limitations Biochemical and cell studies Mechanistic observations and copper-binding experiments
It is hypothesized that palmitoylation of cGAS may impact its signaling pathway in two ways: first, it may increase cGASs binding capacity to dsDNA to promote dimer formation, and second, it may palmitoylate cGAS to improve its dimerization upon DNA recognition (69)
and in the decision to submit the paper for publication
Neutralizes free radicals and prevents cellular oxidative damage
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