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Additionally, subjects with pre-hypertension had significantly higher GGT levels and arterial stiffness than normotensive controls, and pre-hypertensive individuals who developed hypertension over a three-year follow-up period had significantly higher baseline GGT levels than those in whom no such blood pressure variation was registered [49]

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Decreased levels of miR-214-3p have been demonstrated to protect renal TECs from ferroptosis and alleviate tubular damage in cisplatin-induced AKI, as evidenced in both cellular and animal models, by upregulating GPX4 and solute carrier family 7, member 11(SLC7A11) while downregulating Acyl-CoA synthetase long-chain family member 4(ACSL4) expression [160]